2026-06-23-Alexopoulos

Reviewed project overview and current state of analysis. Dr A had several suggestions: - [] repeat group level analysis (Fig 3 from AES poster) using the non-exclusionary EZ/PZ/IZ/NIZ labels.

Commented that it may be more meaningful to see group differences at interictal contacts rather than SOZ contacts, given that MRF is an interictal scan by definition.

Overall, we shouldn’t necessarily expect to see group-level differences. Resection of ther orbitofrontal cortex and insula for example are widely different from cytoarchitecture perspective. May be much worthwhile to take a step back from the SEEG data and look more closely at each individual case - with particular attention to the nonlesional and FCD patients.

Suggested comparing resection cavity T1/T2 against the healthy controls

Could consider looking at resection T1/T2 against nearby peri-resection (i.e. rim of retained tissue) from within the patient as well.

Plan to meet again after above